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. 2019 Sep 12;11(18):7620–7638. doi: 10.18632/aging.102275

Table 2. Promoter analysis of the top 90 hub genes obtained from three modules significant associated with vascular aging status.

Transcription factor NES No. of targets No. o Motifs/Tracks
Pax8 4.484 25 7
Hsf1 4.04 11 1
Pou5f1 3.916 27 2
Ovol1 3.78 14 3
Lef1 3.589 12 4
Zic2 3.485 17 2
Rfx2 3.464 6 3
Egr1 3.433 14 3
Gata2 3.422 12 1
Gltpd1 3.287 11 2
Hic1 3.224 11 3
Zfat 3.212 22 3
Sod1 3.14 4 1
Irf4 3.047 10 1
Mtf1 3.034 11 2

NES: normalized enrichment score