Table 2. Promoter analysis of the top 90 hub genes obtained from three modules significant associated with vascular aging status.
Transcription factor | NES | No. of targets | No. o Motifs/Tracks |
Pax8 | 4.484 | 25 | 7 |
Hsf1 | 4.04 | 11 | 1 |
Pou5f1 | 3.916 | 27 | 2 |
Ovol1 | 3.78 | 14 | 3 |
Lef1 | 3.589 | 12 | 4 |
Zic2 | 3.485 | 17 | 2 |
Rfx2 | 3.464 | 6 | 3 |
Egr1 | 3.433 | 14 | 3 |
Gata2 | 3.422 | 12 | 1 |
Gltpd1 | 3.287 | 11 | 2 |
Hic1 | 3.224 | 11 | 3 |
Zfat | 3.212 | 22 | 3 |
Sod1 | 3.14 | 4 | 1 |
Irf4 | 3.047 | 10 | 1 |
Mtf1 | 3.034 | 11 | 2 |
NES: normalized enrichment score