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. 2019 Sep 18;11(18):7707–7722. doi: 10.18632/aging.102282

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Copyright © 2019 Wang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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RAD51AP1 is upregulated in EGFRvIII-positive cells. The volcano plot was constructed to profile the differentially expressed genes observed in GES46028 (A) and scRNA-seq data (B). (C) A heatmap was employed to profile the differentially expressed genes observed in U87MG/U87MG-EGFRvIII RNA-seq data. A Venn diagram was used to profile the common upregulated (D) and downregulated (E) genes in three databases. (F) The EGFRvIII, r-H2A.x, RAD51AP1 and Ki-67 expression levels in multipoint samples from two patients were examined by IHC staining.