Table 2. Univariate and multivariate cox proportional regression analysis with overall survival.

	Univariate analysis			Multivariate analysis
	HR (95%CI)	P value		HR (95%CI)	P value
Age (years)
≤60	1.000	0.004*		1.000	0.007*
>60	3.191(1.458-6.986)			2.924(1.332-6.419)
TIP-B1
Low	1.000	0.002*		1.000	0.016*
High	3.161(1.529-6.356)			2.502(1.183-5.924)
Gender
Female	1.000	0.875		NA
Male	0.949(0.495-1.821)
Tumor size
≤4cm	1.000	<0.0001*		1.000	0.546
>4cm	3.348(1.702-6.587)			1.983(0.215-18.263)
Laterality
Left	1.000	0.658		NA
Right	1.158(0.606-2.211)
Fuhrman grade
G1-2	1.000	0.445		NA
G3-4	1.289(0.672-2.471)
T stage
I-II	1.000	0.001*		1.000	0.906
III-VI	3.182(1.636-6.189)			1.132(0.145-8.817)
Metastasis
No	1.000	<0.0001*		1.000	0.219
Yes	3.757(1.928-7.322)			2.924(1.332-6.419)

CI: confidence interval, HR: hazard ratio

* statistically significant (p <0.05)

p value from Cox regression analyses