Table 2. Combination index (CI) at ED₅₀ values of drug combination on two bladder cancer cell lines.

Cell line	SIP-SII	AZD4547	CI at ED50
RT112	6.735	1.252	0.7037
JMSU1	7.395	1.280	0.7407

Notes: Bladder cancer cells were treated with various drugs combination as indicated. CI values at 50% effective doses (ED₅₀) were calculated using Chou-Talalay method. Data are the mean of two independent experiments performed in triplicate. SIP-SII, Sulfated polysaccharide of Sepiella maindroni ink.