Table 5.
Cytokines and Chemokines in Male Rats after Exposure to 1080.
| Analyte | Control | 0.85 LD50 | ||
|---|---|---|---|---|
| pg/ml | Standard Deviation | pg/ml | Standard Deviation | |
| G-CSF | 65.3 | 31.0 | 68.4 | 35.2 |
| IFNy | 29.8 | 13.0 | 30.6 | 13.9 |
| IL-1β | 11.2 | 2.3 | 16.9 | 10.4 |
| IL-6 | 2.8 | 2.8 | 4.2 | 4.2 |
| IL-10 | 53.1 | 31.9 | 62.9 | 48.2 |
| GRO-α | 354.5 | 166.3 | 434.8 | 225.2 |
| MCP-1 | 5003.6 | 2559.0 | 4042.6 | 2133.6 |
| MIP-1α | 32.4 | 6.9 | 36.8 | 12.1 |
| MCP-3 | 638.2 | 356.3 | 500.4 | 349.8 |
| MIP-2 | 11.1 | 2.5 | 14.3 | 4.3 |
| TNF-α | 3.8 | 1.0 | 6.2 | 4.3 |
| Eotaxin | 1734.2 | 1253.2 | 1043.4 | 111.9 |
| IL-2 | 10.7 | 3.1 | 25.5 | 25.0 |
| IL-4 | 17.3 | 9.0 | 15.5 | 8.6 |
| IL-5 | 38.6 | 23.3 | 30.0 | 18.5 |
| IL-12 (p70) | 11.5 | 18.9 | 16.9 | 18.2 |
| IL-13 | 3.7 | 0.5 | 6.1 | 4.2 |
| IL-17 | 4.1 | 4.2 | 11.7* | 3.5 |
| IP-10 | 188.4 | 110.0 | 157.6 | 105.3 |
| RANTES | 15364.2 | 3628.2 | 10714.0 | 8749.3 |
n = 8-11,
*
p < 0.05, Student’s t-test. All cytokines and chemokines not listed were below the limit of detection.