Table 1. Univariate analyses of factors associated with VL relapse by 12 months N = 1353.
| Relapse by extended follow up (N = 75) | Cured at extended follow up (N = 1,278) | p value | |
|---|---|---|---|
| n (row %) | n (row %) | ||
| Regimen | |||
| SDA | 45 (6.3) | 665 (93.7) | 0.0002 |
| Amb+Milt | 25 (8.5) | 269 (91.5) | |
| Milt+PM | 5 (1.4) | 344 (98.6) | |
| Sex | |||
| Male | 50 (6.1) | 774 (93.9) | 0.29 |
| Female | 25 (4.7) | 504 (95.3) | |
| Age | |||
| 2–12 years | 34 (7.8) | 400 (92.2) | 0.01 |
| >12 years | 41 (4.5) | 878 (95.5) | |
| Reported length of illness | |||
| ≤8 weeks | 70 (6.5) | 1004 (93.5) | 0.002 |
| >8 weeks | 5 (1.8) | 274 (98.2) | |
| Severe anaemia | |||
| Yes | 22 (4.7) | 451 (95.4) | 0.29 |
| No | 53 (6.0) | 827 (94.0) | |
| Severe wasting | |||
| Yes | 15 (7.3) | 191 (92.7) | 0.24 |
| No | 60 (5.2) | 1,087 (94.8) | |
| ALT ≥ 200 U/L | |||
| Yes | 1 (1.9) | 53 (98.2) | 0.23 |
| No | 74 (5.7) | 1225 (94.3) | |
| AST ≥ 200 U/L | |||
| Yes | 6 (4.3) | 133 (95.7) | 0.5 |
| No | 69 (5.7) | 1,145 (94.3) | |
| Creatinine ≥ 1.5 (units) | |||
| Yes | 2 (6.1) | 31 (93.9) | 0.89 |
| No | 73 (5.5) | 1,247 (94.5) | |
| Patient category | |||
| Primary kala-azar | 69 (5.4) | 1,210 (94.6) | 0.59 |
| Previously treated kala-azar | 4 (8.7) | 42 (91.3) | |
| Transferred | 2 (7.1) | 26 (92.9) |