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Effect of actinomycin D (Act D) or cycloheximide (Cyclohex) on the increase in APP holoprotein stimulated by PGE2. Actinomycin D or cycloheximide (both 2.5 μm) effectively inhibited the increase in APP holoprotein stimulated by PGE2 (10 μm) but had no significant effect on basal APP levels. Graph represents means and SEM from four independent experiments (*p < 0.05).
