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Effect of the immunosuppressant cyclosporin A or FK-506 on cAMP production caused by PGE2 treatment of cultured astrocytes. Cellular cAMP levels stimulated by PGE2 are not inhibited by the immunosuppressant cyclosporin A (CsA) or by FK-506 (both 50 μm). Graph represents means and SEM from a typical experiment conducted on duplicate dishes (*p < 0.05).
