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Alignment of amino acid sequences of wild-type and mutant glycine, and GABAA receptor subunits. Sequences represent the cytoplasmic loop between transmembrane segments M1 and M2 including the flanking regions. The last rowindicates point mutations encoded by the GLRA1 mutant alleles. Positions of transmembrane regions M1 and M2 are marked. The amino acid exchange P250T is given in bold. Sequences were retrieved from the EMBL nucleotide sequence database (http://www.ebi.ac.uk/embl.html).
