Table 1.

Summary of simulation parameters

Train depolarization simulation control parameter set	Time constant	Magnitude
Basal[Ca2+]i		153 nm
Peak [Ca2+]i after initial depolarization in train		871 nm
Caτ1: Primary [Ca2+]i decay after pulses within train	5.5 sec
1-aCaτ2: Fast Ca2+current rundown within train	8.8 sec	137 pA
1-aCaτ3: Slow Ca2+current rundown within train	116.9 sec	253 pA
1-aCaτ4: Fast [Ca2+]i decay after train	22 sec	250 nm
1-aCaτ5: Slow [Ca2+]i decay after train	77 sec	250 nm
a3 value		0.035 μm−3 sec−1
Pool A size		5 pF
a1 value (control)		0.007 sec−1
a1value (activated)		0.014 sec−1
k−1 value		0.031 sec−1
b1 value		1.9 μm

All values either obtained from the literature or measured experimentally in this study.

^F1-aSee legend to figure 5 for description.