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. 1999 May 1;19(9):3423–3429. doi: 10.1523/JNEUROSCI.19-09-03423.1999

Fig. 5.

Fig. 5.

Okadaic acid treatment blocks sumatriptan-mediated inhibition of potassium-stimulated CGRP release. The relative amount of CGRP secreted from trigeminal neurons stimulated with 60 mmKCl, 600 nm (unless indicated as 300 nm) okadaic acid (OA), or the combination of KCl and OA, with or without cotreatment with 10 μm sumatriptan (Suma) is shown. The mean basal rate of CGRP secretion was 99 ± 4 pg/hr per dish. The means and SE from at least three independent experiments are shown. *p < 0.001 when compared with control values. # p < 0.05 when compared with KCl values.+ p < 0.05 when compared with KCl plus sumatriptan values.