Table 1.

cAMP levels in cultured trigeminal neurons

Sample	cAMP (fmol/dish)	Fold increase
Control	354  ± 25
FSK	11283  ± 916*	32
FSK + sumatriptan	10930  ± 1029	31
FSK + CGS	11047  ± 720	31
IFC	364  ± 10	1.0
IFC + sumatriptan	356  ± 18	1.0

cAMP levels were measured from untreated control cultures or cells treated for 30 min with forskolin (FSK) or with a cocktail of inflammatory agents (IFC). The cultures were cotreated with vehicle, sumatriptan, or CGS. The means and SE from five independent experiments with duplicate samples, and the fold increases in cAMP levels relative to control cells are shown.

*p < 0.001 when compared with control levels.