Table 2.
cAMP levels in 5-HT1B-expressing HeLa cells
| Sample | cAMP (fmol/dish) | Fold increase |
|---|---|---|
| Control | 234 ± 8.9 | |
| FSK | 4950 ± 244* | 21 |
| FSK + sumatriptan | 348 ± 26 | 1.5 |
| FSK + CGS | 318 ± 26 | 1.4 |
cAMP levels were measured from untreated control cultures or cells treated for 15 min with forskolin (FSK). The cultures were cotreated with vehicle, sumatriptan, or CGS. The means and SE from two independent experiments with duplicate samples, and the fold increases in cAMP levels relative to control cells are shown.
*p < 0.02 when compared with control levels.