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. 1999 May 1;19(9):3507–3518. doi: 10.1523/JNEUROSCI.19-09-03507.1999

Fig. 7.

Fig. 7.

Transverse sections of the tongue in wild-type (wt), BDNF-transgenic (BDNF tg), and NT-3 transgenic (NT-3 tg) mice.A, Normal appearance of filiform and fungiform papillae (arrow). Note that there is a taste bud within the superior surface epithelium. B, Circumvallate papilla is well developed in wild-type mice and contains many well differentiated taste buds in its superior surface (one taste bud is visible in the midportion of the superior surface epithelium in this photomicrograph).C, In BDNF-transgenic mice there are less fungiform papillae. The fungiform papilla in this photomicrograph is smaller than in wild-type and NT-3 transgenic mice but appears to contain a taste bud. D, Circumvallate papilla has distorted morphology in BDNF-transgenic mice. E, F, Tongue papillae appear normal in NT-3 overproducing Mice. Scale bar:A, represents 100 μm in all panels.