Fig. 8.

Wheel running rhythm of heterozygote tau mutants for which the anatomical data are presented in Figures 6 and 7. The animals received an SCN lesion (SCN-X) and received a half-SCN transplant at the points indicated on theleft of the actogram (see Fig. 4 legend for further details). A, The intact hamster B28-Q66 had a free-running period of 21.9 hr (days 1–8) and became arrhythmic after an SCN lesion (days 12–22). After transplantation, it recovered with the donor period of 24.8 hr (days 43–71). B, The intact hamster B33-Q67 had a period of 21.9 hr (days 1–8). After an SCN lesion, it became arrhythmic (days 12–22). After transplantation, it recovered with the donor period of 24.0 hr (days 61–103).