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Effects of apomorphine administration [0.3 mg/kg (open symbols) and 1.0 mg/kg (filled symbols), s.c.] on locomotor activity in animals with sham (circles) or 6-OHDA (squares) lesions of the nucleus accumbens. The effects of apomorphine administration were significantly enhanced in animals with 6-OHDA lesions of the nucleus accumbens. Asterisks indicate p < 0.05 compared with same-dose sham controls (matched ttest; n = 9/group).
