Table 1.

Tissue dopamine concentrations in rats with 6-OHDA lesions of the nucleus accumbens and in sham-lesioned animals

	Nucleus accumbens	Caudate nucleus
Sham	4.99  ± 0.21	8.35  ± 0.87
Lesion	0.48  ± 0.11***	6.88  ± 0.68

Dopamine concentration is expressed in picograms per milligram wet weight of tissue ± SEM. Dopamine levels in lesioned rats were significantly decreased in the nucleus accumbens but not in the caudate nucleus. Asterisks indicate significantly different from the sham control (p < 0.0001, unpaired ttest).