Fig. 10.

Cholinergic mEPSCs are characterized by rapid activation and decay kinetics. A, A histogram of the 10–90% rise time was generated from 314 events recorded from a single neuron at 7 DIV. The data are fit with a single Gaussian curve with the mean indicated by the arrow. B, The averaged mEPSC in this neuron exhibits a typical rapid decay phase that is well fit by a single exponential distribution with a τ of 1.5 msec. C, A box plot illustrates the variability in the 10–90% rise time and decay time constant for the mEPSCs in the population of neurons examined. The 5th and 95th percentiles are indicated by the whiskers, and the 25th, 50th, and 75th percentile boundaries are indicated by thebox for each group. ▴, Maximum values; ●, minimum values; ▪, the mean.