Fig. 2.

Two classes of kinetically distinct spontaneous synaptic currents recorded from cultured Drosophilaneurons. A, Fast sPSCs recorded from a neuron at 3 DIV, typical of the currents recorded in ∼50% of the wild-type neurons. Holding potential was −75 mV. B, An example of a kinetically distinct class of sPSCs, recorded in a second wild-type neuron at 3 DIV, is characterized by a slow decay time constant. These slow sPSCs are inward when the cell is held at −55 mV and outward at −25 and −5 mV, reversing near the calculated chloride equilibrium potential (−46 mV).