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PKC inhibitors sensitize the photoreceptor and do not appear to affect light adaptation. A, Photocurrents elicited by two 20 msec light flashes (log10 −3.5; 1 sec apart) under voltage-clamp conditions in ASW are shown.B, The response to the first flash is increased in the presence of 25 μm Gö 6976, whereas the second flash is unchanged. C, Receptor potential elicited by a prolonged intense light (log10 −1), after overnight incubation with 25 μm Gö 6976.
