Fig. 1.
Basal synaptic transmission at the Schaffer collateral–CA1 pathway of hippocampal slices is not affected by treatment with TrkB-IgG fusion protein or BDNF antibody. The slope of field EPSPs was plotted against stimulus strength (in microamperes).A, TrkB-IgG fusion protein (triangles,dotted line; n = 7 slices, 4 mice) and controls (diamonds, solid line;n = 8 slices, 4 mice) (p> 0.2). B, BDNF antibody (triangles,dotted line; n = 8 slices, 4 mice) and controls (diamonds, solid line;n = 7 slices, 4 mice) (p> 0.3).