Fig. 6.

C-deletion neuropilin-1 is not a dominant negative receptor component for collapse induced by the semaphorin domain of SEMA-3A. Sympathetic reaggregates were transfected with truncated Trk-B or C-deletion neuropilin-1 and treated with 5 c.u. of the semaphorin domain from Sema-Fc. This truncated form of SEMA-3A that is missing the Ig-basic domains induces growth cone collapse, even in growth cones expressing C-deletion neuropilin-1. The SEM of four experiments is shown for each condition.