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. 1999 Sep 1;19(17):7476–7485. doi: 10.1523/JNEUROSCI.19-17-07476.1999

Fig. 6.

Fig. 6.

Overexpression of Bcl-2 inhibits the redistribution of cytochrome c, but not BAX, in NGF-deprived sympathetic neurons. Neurons from wild-type (▴) orBcl-2 transgenic (●) mice were maintained in NGF for 5 d and then deprived of NGF in the presence of 50 μm BAF for various periods. At 0, 12, 24, or 48 hr after deprivation the cells were fixed and immunostained for BAX (a) or cytochrome c(b); then the number of cells exhibiting punctate BAX or diffuse cytochrome c staining was determined, with 200–250 cells counted for each time point. Mean ± SEM;n ≥ 3.