Fig. 3.

Comparison of DNIC-induced inhibitions triggered by flexion of the arthritic ankle in animals with acute (black columns) or chronic (white columns) monoarthritis. The percentage of inhibition of the C-fiber responses of trigeminal neurons triggered by flexion of the arthritic ankle are represented for each group during flexion and in two successive 22 sec (postconditioning) periods after the cessation of flexion (post-cond 1, post-cond 2). The same maneuver applied to the normal ankle of arthritic or normal rats triggered virtually no inhibition (data not shown). *p < 0.05 for comparison between acute and chronic monoarthritis groups.