Fig. 3.

Comparison of the apNEP (λNEPg1 clone), hNEP, hECE1, hKELL, and hPHEX exons that code for the zinc-binding domain. Nucleotide sequences of exons and flanking introns are shown incapital and small letters, respectively. Splicing consensus sequences are underlined. The deduced amino acid sequence of the apNEP exon is shown above the nucleotide sequence. The codons for identical amino acids are inbold type, and the pentapeptide consensus sequences (His-Glu-Xaa-Xaa-His) that are part of the metalloprotease zinc-binding domain are boxed.