Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inactivation kinetics of I1495F. A, Time constant of fast inactivation for WT (filled circles, n = 39) and I1495F (open circles, n = 14) showing an additional slow component (open squares,n = 14) for the HyperKPP mutant channels.B, Steady-state fast inactivation. HEK 293 cells were subjected to a protocol described in Materials and Methods to generate the inactivation curves for WT (filled circles,n = 43) and I1495F (open circles,n = 31).
