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Under conditions of high [K+]o and low [A−]pip, furosemide shiftedEIPSC to a more negative value.A, Furosemide reduced the amplitude of inward sIPSCs (recorded with 4.5 mm[A−]pip and 8 mm[K+]o). B, In the same cell recorded under identical conditions as inA but at a more positiveVH, furosemide increased the amplitude of outward sIPSCs. Letters mark segments on the chart plots that were shown at higher sweep speed in the lower traces.
