Table 1.
Contralateral | Ipsilateral | Ratio (I/C) | |
---|---|---|---|
WT | 3555 ± 201 | 2470 ± 134 | 70 ± 2 |
KO | 3268 ± 261 | 1840 ± 157 | 57 ± 4* |
Neurons with distinct nucleoli were counted by a blinded observer in every fifth section from contralateral and ipsilateral DRG removed 2 weeks after sciatic nerve transection (mean ± SEM;n = 9 mice in each group). Note that the mean of the ratios is not the same as the ratio of the means. *p < 0.05 by Student’s t test or Mann–Whitney rank sum test. Neuronal counts in the contralateral DRG tended to be lower in IL-6 −/− mice than wild-type mice, but this trend did not reach statistical significance. WT, Wild-type mice; KO, IL-6 −/− mice.