Representative lesions of FN produced by injection of IBO into FN 9 d earlier visualized at low (scale bar, 1.5 mm) and higher (scale bar, 0.125 mm) magnifications. A,B, Naive control. Arrow indicates left FN. Note large Nissl-stained FN neurons at higher power.C, D, IBO treatment. The broken lines outline the area of complete destruction of local neurons with reactive gliosis 9 d after microinjection of IBO. Note loss of large neurons. E, F, The FN 9 d after injection of vehicle. Note accumulation of small stained cells about some neurons.