Table 4.
Values (±SEM) of AP, percentage of increases in rCBF, and change in percentage of baseline CVR
| Group (n) | Peak AP (mmHg) | Peak rCBF (PU as % increase from baseline) | Δ Percentage of baseline CVR |
|---|---|---|---|
| Control stimulation | |||
| Sham stimulated (3) | 90.7 ± 4.8 | 4.3 ± 4.7 | 96.7 ± 7.1 |
| DN stimulated (3) | 96.8 ± 3.2 | 3.0 ± 5.8 | 111.1 ± 9.6 |
| FN stimulation | |||
| Intact (4) | 110.9 ± 6.2 | 34.0 ± 6.0 | 79.0 ± 1.4*§ |
| FN-lesion (4) | 114.0 ± 3.8 | 50.0 ± 7.9 | 75.8 ± 2.7*§ |
| FN-sham-lesion (4) | 110.4 ± 4.5 | 53.0 ± 10.7 | 76.5 ± 7.3*§ |
| DN-lesion (4) | 122.0 ± 7.4 | 93.6 ± 27.1 | 77.8 ± 8.6*§ |
Values (±SEM) of AP, percentage of increases in rCBF, and change in percentage of baseline CVR (absolute millimeters mercury per absolute perfusion units) at peak elevation of rCBF in Sprague Dawley rats evoked by electrical stimulation of the FN in cerebellar-lesioned animals (FN-lesion, DN-lesion), in nonlesioned controls (Intact, FN-sham-lesion), or in nonlesioned animals after control stimulation (DN stimulated, Sham stimulated; data taken at 10 min after the onset of stimulation, a time point that parallels average time after onset of FN stimulation when peak rise in rCBF is elicited). Note that FN stimulation significantly reduces CVR relative to control stimulated groups and that this effect persists after lesion of FN intrinsic neurons.
*p < 0.05 compared with sham- and DN-stimulated controls; ANOVA and SNK test.
§p < 0.05 compared with baseline CVR within group; ANOVA and SNK test.