Fig. 6.

Flies expressing constitutively active protein kinase A in their photoreceptors exhibit slower light responses.A, B, Responses to 10 msec flashes recorded in photoreceptors from transgenic flies expressing constitutively active protein kinase A, PKAact¹(A), and PKAact²(B). UAS-PKAact constructs were targeted to photoreceptors by crossing to flies expressing Gal4 under the control of the Rh1 opsin promoter (Rh1-Gal4). The control responses (PKAact × wOR) are from the progeny of the same UAS-PKAact lines crossed to WT (w Oregon R) flies. C,D, Time-to-peak (C) and time-to-half-decay (D) of macroscopic light responses in photoreceptors from PKAact¹(A; n = 7 cells) and PKAact² (B; n = 5) compared with responses from photoreceptors in the control flies (solid traces; n = 4). *p < 0.05.