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Augmented stereotypic behavior in MA-treated rats in response to a subsequent high-dose injection of MA. MA (10 mg/kg, i.p.) or the vehicle (VEH) was administered every 2 hr for a total of four injections. After 7 d, rats were placed in activity chambers and monitored for a 1 hr habituation period, after which they received an injection of MA, 4.0 mg/kg (A) or 7.5 mg/kg (B), or the vehicle. *Significantly different from VEH/MA-treated rats (p < 0.05).
