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Effects of mutant NF-L (Pro) transgene expression and Bcl-2 overexpression on axonal morphology. Cross sections of L5 motor (ventral root) from 2-week-old and 1-, 2-, 6-, and 15-month-old mice are shown. A–D, Representative sections from each genotype are as indicated. Arrows indicate degenerating axons and invading macrophages. Scale bar, 10 μm.
