Fig. 2.

HD cells in AD did not lose their directional firing properties in response to ULs of LMN. The directional tuning curves of each HD cell are plotted before (solid lines) and immediately after (broken lines) the UL. Notice that some HD cells reduced their firing rate, broadened their tuning width, or shifted their preferred firing direction immediately after ULs.Gray shading indicates the extent of the lesion in each case, at coordinates 4.52 (top) and 4.80 (bottom) mm posterior to bregma. Anatomical diagrams are adapted from the atlas of Paxinos and Watson (1997). SuM, Supramammillary nucleus; ML, medial mammillary nucleus (lateral division); MM, medial mammillary nucleus (medial division); Arc, arcuate hypothalamic nucleus.