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Functional analysis of β subunit homomers. Whole-cell currents were recorded from transfected A293 cells after the application of 1 mm GABA, 1 mm pentobarbital (PB), 10 μm Zn2+, or 10 μm picrotoxin (PTX) from A27.1p93 cells expressing A, β2; B, β3;C, β3β2; D, β2β3β2;E, β3(DNTK); and F, β2(GKER) constructs. Calibration bar:A–D, 200 pA; E, F, 100 pA. All of the cells were voltage-clamped at −40 mV, and each trace is representative of observations made from four to five determinations.
