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. 1999 Aug 15;19(16):6795–6805. doi: 10.1523/JNEUROSCI.19-16-06795.1999

Fig. 3.

Fig. 3.

Cannabinoid receptor activation increases paired-pulse facilitation. a, Paired-pulse facilitation (mean ± SEM) before (gray circles;n = 4) and after (black squares) 5 μm WIN55,212-2. The ratio of the second EPSC (P2) to the first EPSC (P1) is shown as a function of the interpulse interval. At all intervals, paired-pulse facilitation increased after application of 5 μm WIN55,212-2. b, Top, Sample traces showing paired-pulse facilitation at 50 msec before (left) and after (right) application of 1 μm WIN55,212-2. Bottom, Bar graph showing paired-pulse facilitation at 50 msec (mean ± SEM) before (1.70 ± 0.08) and after (2.11 ± 0.17) application of 1 μm WIN55,212-2 (p < 0.01, paired t test;n = 9).