Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A guanylyl cyclase inhibitor reversed the cytoprotective effect of SNAP on serum-deprived PC12 cells. Cells were treated with SNAP (100 μm) plus ODQ (40 μm) in the presence and absence of serum. Cell viability(A), DEVDase activity (B), DNA fragmentation (C), and PARP fragmentation(D) were determined as described in Materials and Methods. Data represent mean ± SD of three experiments. *p < 0.01; **p < 0.05.
