Homomultimerization and heteromultimerization of GRIP1 and GRIP2. a, In cotransfected HEK293T cells, full-length GRIP1 protein could be coimmunoprecipitated with myc-PDZ456 (lane 1) but not with a myc-PDZ45 construct lacking PDZ6 (lane 2). Myc-PDZ456 (lane 12), but not myc-PDZ45 (lane 13), could also be coimmunoprecipitated by anti-GRIP1 antibody.b, Myc-PDZ456, but not myc PDZ45, could be coimmunoprecipitated by HA-PDZ456. c, In transfected 293T cells, full-length GRIP1 coimmunoprecipitated with GRIP2.