Fig. 2.

The current through non-NMDA receptors was not affected by PDC. A, A spiking neuron isolated from the newt retina was voltage-clamped at −80 mV. Both the superfusate and the puff pipette solution included 50 μmd-AP-5 to block the current through NMDA receptors. A 20 msec puff-application (top) of 200 μmglutamate (Glu) induced an inward current.B, The glutamate-induced current was not affected by the presence of 200 μm PDC. C, Application of NBQX (5 μm) to the superfusate completely blocked the response to a 100 msec puff of glutamate.