Table 1.
Strain | Dose (mg/kg, s.c.) | |||
---|---|---|---|---|
60 | 70 | 80 | 90 | |
D2 | 0 ± 0 (7) | 14 ± 7 (14) | 90 ± 7 (20) | 95 ± 5 (19) |
B6 | 0 ± 0 (8) | 0 ± 0 (10) | 0 ± 0 (18)** | 14 ± 13 (15)* |
F1 | 80 ± 10 (15) | |||
F2 | 65 ± 2 (511) |
Values represent the percentage (±SE) of animals exhibiting tonic hindlimb extension. The number in parentheses indicates the number of mice treated.
**p = 0.0014; *p = 0.0046 versus respective D2 value (Fisher’s Exact Test, two-tailed).