Table 6.

PTZ-induced seizure-related loci: multivariate stepwise logistic regression analysis^a

Marker6-b	Coeff ± SE6-c	Wald χ2	pvalue6-d	Odds ratio6-e
D1Mit11	1.87  ± 0.45	17.0	<0.0001	6.50
D1Mit17	1.42  ± 0.45	10.0	0.0015	4.16
D3Mit268	0.88  ± 0.34	6.85	0.0089	2.41
D5Mit398	1.18  ± 0.42	8.19	0.0042	3.25
D6Mit102	1.13  ± 0.33	12.0	0.0005	3.09

^F6-aRegression was conducted with the dependent variable defined as the presence (n = 335) or absence (n = 176) of tonic-clonic seizure activity.

^F6-bMarkers with significant phenotype-predictive value (see Table 5 for markers entered into analysis). Marker data were recoded to reflect the best-fitting mode of inheritance. Results are expressed in terms of the seizure-susceptibility allele.

^F6-cMean regression coefficient (±SEM) for the marker.

^F6-dProbability that the regression coefficient equals 0.00.

^F6-eOdds of expressing a PTZ-induced tonic-clonic seizure when possessing the susceptibility genotype at the indicated marker locus.