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. 1999 Aug 15;19(16):6955–6964. doi: 10.1523/JNEUROSCI.19-16-06955.1999

Fig. 1.

Fig. 1.

Degeneration of NT2-derived neurons infected with an APP695-expressing adenovirus. Neurally differentiated NT2 cells were infected with AxCAYAP.A–E, Phase-contrast micrographs at 0 (A), 48 (B), 72 (C), and 96 (D) hr.E, β-Galactosidase staining of AxCALacZ-infected cells at 96 hr. β-Galactosidase activity was histochemically stained and observed by phase-contrast micrography. Arrowheads, Aggregations of postmitotic neurons. F, Ethidium homodimer staining of AxCAYAP-infected cells at 120 hr.Arrowheads, Positive dead cells; arrows, negative viable cells. Scale bar (in A):A–E, 200 μm; F, 100 μm.