Fig. 6.

Infusion of ephrinA5-IgG in DBA/2 mice improves spontaneous alternation rate in the T-maze (T-CAT paradigm).A, EphrinA5-IgG-treated mice (white bar;n = 19) exhibited higher levels of alternation compared with CD4-IgG-infused mice (black bar;n = 17; t = 2.85; df = 34;p < 0.01). B, Time spent to complete 15 alternation trials did not differ between treatment groups (t = 0.365; df = 34; p > 0.710), suggesting that the improved alternation performance is not caused by motoric or motivational influences. Error bars represent SEM. Methods as in Figure 4 (also see Materials and Methods).