Fig. 7.
Selective loss of LTD in the ACC but not the PC after the amputation. A, Diagram of a cortical slice showing the placement of recording and stimulating electrodes in the PC. B, Repetitive stimulation (1 Hz, 15 min; open bar) induced a long-lasting depression of synaptic response in sham animals (open squares; n = 3; 27.6 ± 6.3% of control; p < 0.01). At 45 min after amputation of the third hindpaw digit, similar LTD was induced in slices of PC (filled squares;n = 4; 24.0 ± 11.0%). C, The amputation produced a selective loss of LTD in the ACC but not the PC areas in the same cortical slices.