Fig. 1.

Infusion of ActD into the left IN inhibited eyeblink conditioning (left eye). Graph shows average percent CRs for control (n = 5) and experimental (n = 7) animals. All subjects were trained with only 10 paired CS–US trials per day. The control group (●) received ACSF infusion for the first 5 training days, 1 ng of ActD on the sixth training day (▴), and 1 μg of muscimol on day 7 (▪). The experimental group (▴) received infusion of 1 ng of ActD each day for 5 d. After 2 d rest, experimental animals were trained without drug infusion for 5 more days (○). At day 11, the experimental group was infused with 1 μg of muscimol (▪).