Fig. 3.

Dose-dependent effect of hCB1 cDNA on signaling by receptors for norepinephrine and somatostatin. Bar graph of control Ca²⁺ current inhibition by norepinephrine (NE, open bars) and somatostatin (SOM, diagonal bars) in uninjected SCG neurons (Uninjected) and in neurons microinjected with 10, 50, and 100 ng/μl hCB1 cDNA (hCB1). Microinjection of 50 ng/μl hCB1 cDNA significantly reduced (*p < 0.05) the inhibition of the Ca²⁺ current by both norepinephrine and somatostatin. Microinjection of 100 ng/μl hCB1 cDNA abolished (**p < 0.001) the inhibition of the Ca²⁺ current by both norepinephrine and somatostatin. The number of neurons tested is indicated.