Table 1.

Summary of micro-CALI of L1 and NCAM effects

Treatment	Neurite retraction	Local growth cone collapse
CALI of L1 (8D9)	10 /12	1 /12
CALI of L1 (intra L1)	8 /12	0 /12
CALI of NCAM-180 (4d)	0 /25	21 /25
CALI of NCAM (5e)	0 /20	3 /20
CALI of L1 & NCAM-180 (8D9 & 4d)	12 /13	10 /13
CALI using IgG	0 /20	2 /20
CALI using BSA	0 /12	1 /12
No treatment	0 /13	0 /13

DRG neurites were treated with micro-CALI of L1, NCAM-180, both together, or a variety of controls. Growth cone motility and neurite outgrowth were assessed, and neurons were deemed to undergo neurite retraction if the neurite decreased in length after laser irradiation and increased in length before irradiation. Neurons were deemed to show local growth cone collapse when a net decrease in filopodial length was observed within the laser spot, and there was a net increase in filopodial length in the rest of the growth cone and within the chosen laser spot before irradiation.