Fig. 7.

GABA_ARs are not required for the actions of DAMGO. Shown are electrophysiological recordings of spontaneous burst activity in a cultured hippocampal neuron under baseline control conditions (5 μm NBQX is present to block AMPARs) and after the addition of the GABA_AR antagonist picrotoxin to the bath saline, followed by the subsequent addition of 1 μm DAMGO (NBQX and picrotoxin are still present). In the presence of NBQX and picrotoxin, DAMGO still enhanced the amplitude and spike number of spontaneous burst events.