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DAMGO enhances Ca2+ spiking.A, B, Voltage responses elicited by intracellular application of two depolarizing (+150 and +250 pA) and two hyperpolarizing (−30 and −50 pA) current pulses in a hippocampal neuron under control conditions and after the addition of DAMGO to the bath saline. TTX, NBQX, and picrotoxin were present in the bath saline. DAMGO increased the Ca2+ spiking elicited by the depolarizing current pulses.
